Name: Comfort Inn & Suites Sikeston I-55
Address: 109 Matthews Lane, Sikeston, Missouri, 63801
Price range: US$108+

Comfort Inn & Suites Sikeston I-55 Exterior photo

Key details

About the Hotel

109 Matthews Lane, Sikeston, 63801

Close to the Sikeston Depot Museum & Gallery

Very good

7.9

8.1

/10

3.5

3.6

4-star pet-friendly hotel with indoor heated pool and hot tub in Sikeston

Amenities

The hotel offers an indoor heated swimming pool and spa facilities open year-round. A complimentary American breakfast is served daily with waffles, sausage, eggs, biscuits and gravy, cereal, muffins, and yogurt. Free high-speed Wi-Fi is available throughout the property.

Rooms

Guest rooms include King Suites and Queen Rooms with two queen beds, all non-smoking. Accessible rooms with walk-in showers and extra space are available for wheelchair users. The hotel provides room types suitable for families and business travelers.

Location

The hotel is near Bootheel Golf Club, a public golf course in Sikeston. Historic Sikeston Depot, a former railroad station turned museum, is a short drive away. Veterans Park offers outdoor recreation and is within walking distance.

Business

A business center with copy and fax services is available for guests. Free high-speed Wi-Fi supports remote work needs. The quiet location away from the highway helps with restful stays for business travelers.

Pet-Friendly

The hotel allows pets with a small fee, making it suitable for travelers with animals. Pet-friendly rooms are offered at reasonable rates. Ample on-site parking includes space for larger vehicles.

Highlights

Amenities: Indoor heated pool and hot tub

Rooms: King Suites and Queen Rooms with accessible options

Location: Near Bootheel Golf Club and Historic Sikeston Depot

Business: Business center with copy and fax services

Pet-Friendly: Pets allowed with reasonable fee and ample parking

Breakfast: Complimentary American breakfast daily

Must-do experiences

Savor a slice of famous Scott's BBQ for a true local flavor.
Visit the Sikeston Depot Museum for a glimpse into local history.
Catch a live performance at the historic Prophecy Palace Theatre.
Explore Sikeston's Farmers Market on Saturdays for fresh produce.
Discover the quaint shops at the Old Town Mall for unique finds.

Select your room type

Comfort Inn & Suites Sikeston I-55 offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals

King Room Non-Smoking
2 persons
360 sq. feet
1 King-size bed
room details
King Suite Non-Smoking
2 persons
360 sq. feet
1 King-size bed
room details
Queen Room Two Queen Beds Non-Smoking
2 persons
360 sq. feet
2 Queen Size Beds
room details

Show all rooms

Price and Room Availability Calendar

Check availability and prices for your dates now!

Facilities

Comfort Inn & Suites Sikeston I-55 offers amenities for your comfortable stay and unforgettable experiences

Facilities: Very good

7.9/10Review score

General

Wi-Fi
Parking
Safe deposit box
Pets allowed

Children

Cots

Spa & Leisure

Indoor swimming pool

Bathroom

Washing machine

Media

AM/FM alarm clock

Comfort Inn & Suites Sikeston I-55 Location

109 Matthews Lane, Sikeston, 63801

Map view

City landmarks

Landmark

Malco Sikeston Cinema and Grill

2.1 mi

Landmark

Cheers Bar & Grille

1.8 mi

Landmark

Kingdom Hall of Jehovah's Witnesses

1.9 mi

Landmark

Boot Heel Golf Club

2.0 mi

Landmark

Sikeston Jaycee Bootheel Rodeo

2.0 mi

Landmark

Malco

2.1 mi

Gallery

Sikeston Depot Museum & Gallery

3.1 mi

Landmark

Bement Church

2.7 mi

Landmark

Sikeston Sports Complex

2.7 mi

Landmark

Malco Sikeston Cinema

3.0 mi

Landmark

Central Park

2.9 mi

Landmark

Sikeston Missouri Arts

3.1 mi

Restaurants

Jd's Steakhouse & Saloon

3400 ft

4 N Interstate Dr

Explore Sikeston

Malco Sikeston Cinema & Grill

10-minute drive

A popular cinema offering the latest movies with comfortable seating and a full dining menu for a complete entertainment experience.

Sikeston Depot Museum & Gallery

15-minute drive

A historical museum showcasing Sikeston's railroad heritage, featuring local artifacts and interesting exhibits for all ages.

Sikeston Jaycee Bootheel Rodeo

10-minute drive

An annual rodeo event featuring thrilling bull riding and rodeo competitions, perfect for an exciting summer outing.

Boot Heel Golf Club

10-minute drive

A scenic golf course offering a challenging layout for golf enthusiasts, complemented by a relaxed, welcoming atmosphere.

Sikeston Sports Complex

10-minute drive

A family-friendly sports venue with various fields and courts for soccer and baseball, perfect for exercising and fun.

Relaxation at Local Parks

10-minute drive

Several parks in Sikeston offer serene walking trails and picnic areas, ideal for a relaxing day outdoors with nature.

Jd's Steakhouse & Saloon

13-minute walk

A laid-back steakhouse known for its prime cuts and hearty sides, offering a cozy atmosphere great for family gatherings.

Cheers Bar & Grille

10-minute drive

An inviting eatery featuring American classics and a vibrant bar scene with great daily specials, perfect for casual dining.

Malco Sikeston Cinema

10-minute drive

A local cinema featuring the latest films and a cozy atmosphere for a great movie night out with friends or family.

Bootheel Bar

10-minute drive

A lively bar known for its friendly vibe, featuring live music and events. An excellent place for socializing and entertainment.

Getting around

City Centre
Sikeston 8 min · 3.0 mi
Airports
Cape Girardeau Regional (CGI) 65 min · 26.7 mi
Barkley Regional (PAH) 135 min · 55.9 mi

Want to see Exclusive Early Booking Rate?

Get exclusive rates right now!

Check Rates

Property information and rules

Check-in

from 14:00-23:59

Check-out

until 11 am

Internet

Wireless internet is available in the entire hotel for free.

Breakfast

A buffet breakfast is served at affordable prices.

Children & extra beds

There are no cots provided in a room.

Pets

Pets are allowed on request.

Year renovated:

2007

Number of rooms:

Reviews and Ratings

Feedback about Comfort Inn & Suites Sikeston I-55 from previous guests about their experience.

Cleanliness

8.1/10

Comfort

8.2/10

Facilities

7.9/10

Free Wi-Fi

6.4/10

Location

8.7/10

Staff

8.6/10

Value for money

7.9/10

No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.

Open reviews

Show more reviews

Next best alternative

Consider them for your next trip.

Comfort Inn Poplar Bluff North

Poplar Bluff, United States

6.476 reviews

106 USD/night

Econo Lodge Inn & Suites Corpus Christi

Corpus Christi, United States

7.263 reviews

59 USD/night

Quality Inn Dyersburg I-155

Dyersburg, United States

7.542 reviews

71 USD/night

Comfort Suites Jackson-Cape Girardeau

Jackson, United States

7.062 reviews

133 USD/night

Quality Suites Paducah I-24

Paducah, United States

6.277 reviews

119 USD/night

Sleep Inn At Discovery Park Of America

Union City, United States

8.537 reviews

144 USD/night

Quality Inn & Suites Benton - Draffenville

Draffenville, United States

7.859 reviews

75 USD/night

Quality Inn & Suites Metropolis I-24

Metropolis, United States

6.556 reviews

156 USD/night

Sleep Inn & Suites Conference Center Eau Claire North

Union, United States

8.350 reviews

74 USD/night

Econo Lodge & Suites Brinkley

Brinkley, United States

6.644 reviews

57 USD/night

Rodeway Inn Cadiz

Cadiz, United States

8.456 reviews

66 USD/night

Studio Z, An Ascend Collection Hotel

Saint Robert, United States

8.431 reviews

79 USD/night

Popular hotels all over the world

Find your perfect hotel stay today

6.4/10193 reviews

Hotel Mary's Motel Golden

Golden, Canada

Canadian Rockies location, Seasonal outdoor pool

View hotel

7.5/1091 reviews

Hotel Heron's Landing Hotel

Campbell River, Canada

5 min drive to Campbell River, Balcony in every room

View hotel

8.9/10

Hotel Kasa Capitol Hill Downtown Nashville

Nashville, United States

400 m from city centre, 600 m from Ryman Auditorium

View hotel

Hotel Royal Inn Hotel

16 km from Indian Institute of Technology, Bombay, 19 km from Powai Lake

The Huntington Hotel

Nob Hill Spa with 10 treatment rooms, Indoor infinity pool

Centara Mirage Lagoon Maldives - Free Round Trip Speedboat When Stay 4 Nights Or More Between 17 April - 15 October 2026 Hotel

Aqua park with waterslides, Private beach area

Aaj Haveli Udaipur

Pichola Lake Facing Hotel, 37 km from Maharana Pratap Airport

The Continent Hotel Bangkok By Compass Hospitality Bangkok Thailand

1-minute walk to Asok BTS Station, Rooftop pool with city views

The Ox Pub & Rooms Poole Hotel

2 km from Poole Beach

Comfort Inn & Suites Sikeston I-55, Sikeston

About the Hotel

Amenities

Rooms

Location

Business

Pet-Friendly

Highlights

Must-do experiences

Select your room type

Price and Room Availability Calendar

Facilities

General

Children

Spa & Leisure

Bathroom

Media

Comfort Inn & Suites Sikeston I-55 Location

Reviews and Ratings

Next best alternative

Popular hotels all over the world