Comfort Inn & Suites - Hannibal Exterior photoComfort Inn & Suites - Hannibal Exterior photoComfort Inn & Suites - Hannibal Exterior photo
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From119US$ /night
Check-in
20Jun2026Select date
Check-out
21Jun2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4000 Market Street, Hannibal, Missouri, United States, 63401
-
Close to Huckleberry Park
Very good
7.7
7.3
/10
3.3
3.3
/5

Newly renovated hotel with indoor heated pool in Hannibal

Amenities

The hotel has an indoor heated pool and a whirlpool for guest relaxation. A 24-hour fitness center and a business center are on-site for active guests and professionals. Free parking and laundry facilities are available for extended stays.

Rooms

All rooms are newly renovated and include a refrigerator and flat-screen TV. Pet-friendly rooms are available for travelers with animals. The property is completely smoke-free for a healthy environment.

Location & Attractions

The hotel is close to Rockcliffe Mansion, the Mark Twain Riverboat, and the Mark Twain Boyhood Home and Museum. Guests can take unique antique trolley rides through the historic city. The Mississippi River and nearby nature preserves are minutes away.

Wellness & Spa

An indulgent spa and wellness center on-site provides treatments and relaxation options. The indoor whirlpool and heated pool offer additional ways to unwind. A 24-hour gym with modern equipment is open to all guests.

Dining

A full-service hot breakfast buffet is included daily with options like biscuits, gravy, eggs, and waffles. Convenient grab-and-go breakfast items are also provided each morning. Nearby TJ's Supper Club offers gourmet dinners and cocktails.

Highlights

Amenities: Indoor heated pool & whirlpool, 24-hour gym

Rooms: Newly renovated, refrigerators, pet-friendly

Location: Near Rockcliffe Mansion & Mark Twain Riverboat

Dining: Free hot breakfast buffet with grab-and-go options

Wellness: On-site spa and wellness center

Business: Business center and free WiFi

Must-do experiences

  • Visit the Mark Twain Boyhood Home for an insightful historical tour.
  • Try the famous toasted ravioli at La Bamba for a local favorite.
  • Stroll through Riverview Park for stunning views of the Mississippi River.
  • Explore the Hannibal History Museum for fascinating local artifacts.
  • Catch a riverboat cruise for scenic sights and a unique perspective.
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Select your room type

Comfort Inn & Suites - Hannibal offers a variety of rooms including double rooms, family rooms, and suites with breakfast, free cancelations, and special deals
Efficiency King Suite Non Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
King Suite Sofa Bed Non-Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Air conditioning
Efficiency King Suite Sofa Bed Non-Smoking
2 persons
305 sq. feet 
1 King-size bed and 1 Sofa bed
Air conditioning
Queen Room Two Queen Beds Non-Smoking
2 persons
305 sq. feet 
2 King Size Beds
Air conditioning
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Facilities

Comfort Inn & Suites - Hannibal offers amenities for your comfortable stay and unforgettable experiences
Facilities: Very good
7.7/10Review score

General

  • No smoking on site
  • Internet access
  • Free parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Cycling
  • Bowling
  • Golf course
  • Fishing

Services

  • Housekeeping
  • Laundry

Dining

  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room
  • Spa & wellness centre
  • Jacuzzi
  • Shallow end

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
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Comfort Inn & Suites - Hannibal Location

4000 Market Street, Hannibal, Missouri, United States, 63401
Map view
4000 Market Street, Hannibal, Missouri, United States, 63401
Nearby
Oakwood Christian Church
2500 ft
Prince Avenue Baptist Church
2900 ft
Church of Christ
3200 ft
Explore Hannibal
Activities Near Comfort Inn & Suites - Hannibal
Top Attractions
Activities
Dining
Entertainment
Huckleberry Park
18 minutes walking
A scenic park featuring walking trails, picnic areas, and playgrounds, ideal for families. Enjoy its lush surroundings and relaxation.
Mark Twain Boyhood Home and Museum
10-minute drive
The historical home of author Mark Twain, offering insightful tours and exhibitions on his life and works, perfect for literature lovers.
Rockcliffe Mansion
10-minute drive
A stunning historic site showcasing Victorian architecture, with guided tours available. Features beautiful gardens and panoramic river views.
Sodalis Nature Preserve
35 minutes walking
A serene nature preserve offering trails and wildlife observation. Perfect for relaxation and connection with nature.
Hiking at Glascock's Landing
10-minute drive
Thrill-seekers can enjoy scenic trails and river views while hiking. Accessible trails for various skill levels.
LaBinnah Bistro
5-minute drive
A cozy restaurant specializing in farm-to-table cuisine, with vegetarian options. Known for its artisanal dishes and elegant ambiance.
The Brick Oven
10-minute drive
A casual dining spot famous for its delicious pizzas and pastas. Family-friendly atmosphere with outdoor seating available.
Circus Maximus Theater
10-minute drive
Offers a variety of movies and events. Family-friendly atmosphere with comfortable seating and reasonable ticket prices.
The Talking Horse
10-minute drive
A lively bar featuring live music and entertainment. Great for a night out with friends or relaxing after a busy day.
Getting around
City Centre
Hannibal7 min  ·  2.8 mi
Airports
Quincy Regional (UIN)74 min  ·  30.3 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Public parking is possible on site for free.
Internet
High-speed internet access is available in for free.
Breakfast
A buffet breakfast is served and charges are applicable. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2006
Number of rooms:
74
Former name
Holiday Inn Express Hotel And Suites Hannibal

Reviews and Ratings

Feedback about Comfort Inn & Suites - Hannibal from previous guests about their experience.
Review score
Based on 271 verified reviews
7.2/10
Very good
64%
Recommend
Cleanliness
8.0/10
Comfort
8.0/10
Facilities
7.7/10
Free Wi-Fi
10.0/10
Location
8.6/10
Staff
8.3/10
Value for money
7.8/10
Guest reviews
based on 251 reviews
7.7/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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Check-in
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Rooms and Guests2 Guests, 1 Room